American Cellular Labs BCAA XTREME 8-2-2 Ratio

American Cellular Labs

$ 69.99

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12 grams per scoop 8-2-2 ratio 

In order for protein balance to become positive post workout, dietary protein, specifically the amino acid leucine, must be consumed and protein balance will remain negative until it is consumed.3,4

Leucine is one of the three branched chain amino acids (BCAAs) and is unique in its ability to stimulate skeletal muscle protein synthesis. In fact, leucine has about a 10 fold greater impact on protein synthesis than any other amino acid!

So how does leucine stimulate skeletal muscle protein synthesis? Well first we need to understand more about the pathway that leucine activates. It has been shown that leucine activates a major complex in the anabolic pathway called the mammalian target of rapamycin (mTOR).5 Think of mTOR as the amino acid sensor of the cell. mTOR is sensitive to leucine concentrations.

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"mTOR" stands for Mammalian Target of Rapamycin, one of the body's protein synthesis regulators, energy sensors, and nutrient sensors of amino acid availability, specifically of leucine. mTOR is activated when ATP levels are high, and blocked when ATP levels are decreased. mTOR activation is vital for skeletal muscle hypertrophy.

Decreasing leucine concentrations signal to mTOR that there is not enough dietary protein present to synthesize new skeletal muscle protein and it is deactivated. As leucine concentrations increase, it signals to mTOR that there is sufficient dietary protein to synthesize new skeletal muscle protein and mTOR is activated.


Though researchers are not sure exactly how leucine activates mTOR, it has been shown that mTOR is sensitive to leucine concentrations and ATP levels (decreasing ATP levels can also reduce the activation of mTOR).6,7

Activation of mTOR is strongly associated with increased protein synthesis. mTOR increases protein synthesis through two different mechanisms.

The only BCAA with a high concentration of Leucine